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Human Capital Services

Fellow (Post Doc) - PBPK Modeling & Risk Assessment

Apply now Department: 3670080020 Anatomy & Physiology
Job no: 508004
Work type: Post Doc (Term)
Location: Manhattan, Kansas
Categories: Research / Scientific / Grants, Veterinary Medicine
Pay Grade: 001

About this Role:

The Institute of Computational Comparative Medicine (ICCM) and Department of Anatomy and Physiology within College of Veterinary Medicine are seeking applicants for a Fellow (Post Doc) to work in the Computational Toxicology, Pharmacokinetic Modeling, and Risk Assessment Laboratory. The incumbent of this position will be responsible for designing and developing computational models, primarily physiologically based pharmacokinetic (PBPK) models for drugs, environmental chemicals, or nanoparticles in animals or humans for use in food safety and risk assessment to improve public health decision making.

We Support Diversity and Inclusion:

Kansas State University embraces diversity, and promotes inclusion in every sector of the institution. The university actively seeks candidates whose commitments and contributions will advance the University's commitment to the Principles of Community. 

Duties / Responsibilities:

The incumbent of this position will be mainly responsible for the development and applications of computational models, primarily physiologically based pharmacokinetic (PBPK) models for use in food safety and risk assessment to improve public health decision making. Specific responsibilities include:

  • To design and develop PBPK models for drugs in food-producing animals, including swine, beef cattle, dairy cows, sheep, goats, or chickens
  • To design and develop PBPK models for environmental chemicals or nanoparticles in rodents and humans
  • To convert the developed PBPK models to web-based interfaces
  • To apply the developed PBPK models to help address issues related to food safety and risk assessment.

Other responsibilities include:

  • Present research findings in professional conferences, such as Society of Toxicology, Food Animal Residue Avoidance Databank (FARAD) Annual Summit, and American Academy of Veterinary Pharmacology and Therapeutics
  • Write manuscripts toward publication in high quality peer-reviewed journals in the field of pharmacology and toxicology
  • Help prepare documents for grant applications and progress reports
  • Collaborate with other lab members and help on other computational modeling projects that are active in the lab, including quantitative systems pharmacology modeling projects, population-based nonlinear mixed effects pharmacokinetic (popPK or NLME-PK) modeling projects, and probabilistic risk assessment projects.

Required Minimum Qualifications:

  • Ph.D. in pharmacology, toxicology, epidemiology, biostatistics, environmental health, pharmacometrics, bioinformatics, engineering, data science, computer science, or a related field by time of appointment
  • Interest in computational modeling and data analysis
  • Willing to learn new knowledge and skills
  • Good verbal and written English skills

Preferred Qualifications:

  • Ph.D. in which dissertation research was related to pharmacokinetic, systems pharmacology, pharmacometric, biostatistical, or bioinformatic modeling
  • Experience doing physiologically based pharmacokinetic (PBPK) modeling, quantitative systems pharmacology (QSP) modeling, population pharmacokinetic (popPK) modeling, dose-response modeling, biostatistical analysis of epidemiology/toxicology data, metabolomics analysis, or other relevant computational modeling and quantitative analysis skills
  • Experience with one of the following software programs, including Berkeley Madonna, R language, MATLAB, Systems Biology Markup Language (SBML), Pharmacometrics Markup Language (PharmML), acslX, Phoenix, PK-Sim, MoBi, Simcyp, or GastroPlus
  • Ability to professionally interact with collaborating scientists involved in these projects

Special Instructions to Applicants:

Please submit cover letter, resume, and contact information for three professional references 

Screening of Applications Begins:

Screening of applications begins February 17, 2020

Salary Range / Pay Rate:

$ 47,476 - $ 65,000 annual salary

Equal Employment Opportunity:

Kansas State University is an Equal Opportunity Employer of individuals with disabilities and protected veterans and actively seeks diversity among its employees.

Background Screening Statement:

In connection with your application for employment, Kansas State University will procure a Background Screen on you as part of the process of considering your candidacy as an employee. 

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