About This Role:

The department of Diagnostic Medicine and Pathobiology within the College of Veterinary Medicine is seeking applicants for a Fellow (Post Doc). The postdoctoral fellow will be responsible for conducting research in applying multiple cutting-edge selection techniques to synthetic and immune phage display antibody systems to independently perform antibody screening to identify biotherapeutic molecules. Additional areas of research will involve the validation of identified candidate molecules to determine binding properties and functional characterization. Previous hands-on experience in molecular and cell biology, immunology, vaccinology, and animal husbandry is required.

Duties/Responsibilities

• Utilize new knowledge, and contemporary technology and approaches to rationally design and implement high-throughput development of biotherapeutics. Design, generate, and quality control validate antibody display libraries. Hands-on skills on antibody production and purification, screening B cells to identify and subclone candidate antibody genes into expression vectors, and generation of recombinant antibodies. Characterize antibody binding properties using various assays, such as ELISA, FACS, epitope binding, reporter gene assays, biological assays such as ADCC/Complement-mediated target lysis. Design and improve binders through affinity maturation and humanization, and conduct assays to validate potential binders in-vitro and in-vivo.
• Participate in planning experiments. Data analysis and interpretation. Generate technical reports and manuscripts. Participate in research proposal development.
• Train new students and provide oversight of daily programmatic activities. Ensure compliance with IBC [Federal and University] regulations that govern research at BSL-2 level and IACUC.

Why Join Us:

Kansas State University offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, paid time off – vacation, sick, and holidays.   To see what benefits are available, please visit:  https://www.k-state.edu/hcs/benefits

We Support Diversity and Inclusion:

Kansas State University embraces diversity and inclusion.  The university actively seeks individuals who foster a collegial environment and cooperative interactions with coworkers, students, and others.  The University is dedicated to promoting the Principles of Community.

What You’ll Need to Succeed:

Minimum Qualifications:

• PhD training in Molecular Biology/Immunology/Vaccinology.
• Hands-on experience in generation and affinity purification of recombinant proteins using mammalian cells/insect cells/yeast, animal (cattle/rabbits) immunizations, hands-on experience using antibody phage display system and biopanning.

Preferred Qualifications:

• Experience in antibody discovery technologies:
  - Utilize and execute antibody phage display system.
  - Hands-on skills in antibody production in animals.
  - Skills in bioinformatics and FACS.
  - Proposal development.
  - Excellent oral and written communication skills.

Applicants must be currently authorized to work in the United States at the time of employment.

How to Apply:

Please submit the following documents:

1. Resume
2. Cover letter
3. Contact information for three professional references

Screening of Applications Begins:

Screening begins immediately and continues until the position is filled.

Anticipated Hiring Salary Range:

$47,476 - $56,952

Equal Employment Opportunity:

Kansas State University is an Equal Opportunity Employer.  All applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender, gender identity, age, national origin, disability or status as a protected veteran.

Background Screening Statement:

In connection with your application for employment, Kansas State University will procure a Background Screen on you as part of the process of considering your candidacy as an employee.