|About this Role:
||The College of Veterinary Medicine is seeking a Senior Research Associate for independent research involving viruses such as influenza, Foot and Mouth Disease Virus, African swine fever virus, Rift Valley fever virus, Vesicular Stomatis Virus and other select agents. Includes investigating pathogenesis and transmission of foreign animal diseases including foot-and-mouth disease and African swine fever, development of DIVA compatible vaccines for ASF in pigs, a universal vaccine for influenza, pen-side diagnostic development with POCKIT/PCR platform, MAPIA diagnostics, and monoclonal antibody development to select agent recombinant proteins. This position is part of a very busy, successful research team whose main goal is to develop rationally designed vaccines and diagnostics against high-consequence foreign animal, emerging and zoonotic disease threats such as Foot and Mouth Disease, Rift Valley fever virus, African swine fever virus, and highly pathogenic avian influenza virus. The position requires the individual to display critical thinking and independent judgement as it relates to ongoing and new molecular, viral research with direct guidance from Research Science Manager and Primary Investigator. The research is conducted at the BSL2 and BSL3 level of containment including post-mortem necropsies, immunomicroscopy, and transcriptomic studies and utilizes several select target animal models such as pigs, cows, chickens and mice. The position requires the acquisition and maintenance of a DOJ Select Agent clearance.
This position will require the individual to move to New York State and work at Plum Island Animal Disease Center (PIADC) for several months to years for ongoing animal research studies.
|We Support Diversity and Inclusion:
||Kansas State University embraces diversity, and promotes inclusion in every sector of the institution. The university actively seeks candidates whose commitments and contributions will advance the University's commitment to the Principles of Community.
|Duties / Responsibilities:
- Provide expertise technical support in recombinant DNA technology, molecular biology techniques such as RT-PCR, PCR
- Expression and affinity purification of recombinant proteins using mammalian cells/insect cells/yeast/E.coli
- Generate/manipulate live vectors [human adenovirus/VSV/Lentivirus] for vaccine development
- Generate virus-like particles [VLPs], investigate VLPs for vaccine development using serological techniques, develop diagnostic tests or assays
- Quality control validate recombinant live-vectored/protein/VLP-based prototype vaccines
- Work with animals (cows, sheep, pigs and mice- inoculation/bleeding/isolation of peripheral blood mononuclear cells and serum)
- Establish and maintain primary fibroblasts from biopsies/tissues samples
- Generate monoclonal antibodies to select agent recombinant proteins
- Develop, plan, and record experiments
- Write and edit manuscripts and/or articles for publications and/or presentations
- Process and prepare experimental data for statistical analysis
- Hands-on training of new students/visiting scholars/collaborators
- Provide oversight of daily programmatic activities
- Provide lab management support (lab inventory/manage lab sample repositories), and ensure compliance with university regulations
|Required Minimum Qualifications:
- Masters degree
- Two years relevant experience
- DVM with Masters or PhD in molecular biology, virology, or related field
- Scientific publications of current or past research projects
- Ability to work with animals in the BSL2 and BSL3 level of biocontainment
- Five (5) years of Molecular laboratory experience – PCR, RT-PCR, cloning, cell culture techniques, western blotting, affinity purification of recombinant proteins using eukaryotic/prokaryotic cells or cell-free systems,conducting safety and immunogenicity studies, immunological assays, virological assays, poster presentations and/or presentation at local, university or national meetings
- Five (5) years of hands-on experience generating live-vectored subunit vaccines, generation and affinity purification of recombinant proteins using eukaryotic/prokaryotic cells or cell-free systems, cell culture techniques, conducting safety and immunogenicity studies in cattle, sheep, pigs, and/or mice hands-on experience conducting, conducting EliSpot assays in mammals or other immunological assays, flow cytometric techniques, PCR, RT-PCR, reverse genetic systems, plaque assays, hemaggutination assay, monoclonal antibody production in mice, manuscript editing, poster presentations and/or presentation at local, university or national meetings, published articles in nationally/globally recognized scientific journals
|Special Instructions to Applicants:
||Please submit an application along with a cover letter, resume and contact information for three professional references.
|Screening of Applications Begins:
||Screening of applications begins immediately
|Salary Range / Pay Rate:
||$ 44,150 - $ 77,250 annual salary
|Equal Employment Opportunity:
||Kansas State University is an Equal Opportunity Employer of individuals with disabilities and protected veterans and actively seeks diversity among its employees.
|Background Screening Statement:
||In connection with your application for employment, Kansas State University will procure a Background Screen on you as part of the process of considering your candidacy as an employee.